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Article – Journal of Nanoscience and Technology

Journal of Nanoscience and Technology, Volume 2,Issue 2,2016 Pages 76-80

A Facile Phyto-Mediated Synthesis of Gold Nanoparticles using Aqueous Extract of Momordica cochinchinensis Rhizome and Their Biological Activities
A. Lakshmanan, C. Umamaheswari, N.S. Nagarajan*

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In the present study, plant mediated synthesis of gold nanoparticles (AuNPs) using aqueous extract of Momordica cochinchinensis rhizome at room temperature as a reducing as well as a stabilizing agent is reported. The gold nanoparticles synthesized by a green chemical approach were characterized by UV–visible spectroscopy; Transmission Electron Microscopy (TEM), Energy Dispersive X-ray (EDX), X-ray Diffraction (XRD) and Fourier transform infrared (FT-IR) spectroscopy. The formation of AuNPs, observed by colour changes from yellow to ruby red is confirmed by UV–visible spectroscopy showing surface plasma resonance band that at 535 nm. The crystalline nature of the AuNPs formed as face centered cubic structure is evident from the selected area electron diffraction (SAED) and XRD pattern. FT-IR spectrum showed the presence of different biomolecules in the Momordica cochinchinensis rhizomes aqueous extract responsible for the reduction and stabilization of AuNPs. Phytosynthesized AuNPs showed better antioxidant activity than the aqueous extract when analysed by using DPPH, NO, H2O2 and reducing power assay methods. Moreover, the biosynthesized AuNPs significantly inhibited the growth of medically important pathogenic gram positive bacteria and gram negative bacteria.

Keywords: Gold Nanoparticles; Momordica cochinchinensis; Antioxidant; Antibacterial Activity;

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