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Article – Journal of Nanoscience and Technology

Journal of Nanoscience and Technology, Volume 3,Issue 1,2017 Pages 237-239

Nanosization of Drug Biomaterials and Its Solubility Enhancement by High Energy Ball Milling
S. Thamizharasan*, N. Anbu Saravanan

To evaluate the solubility enhancement of plant derived drugs in the form of nanosized biomaterials. Nanosization obtained from biomaterial sample of marine macro alga Padina gymosphora, using high energy ball milling technique and structural characteristic studies of biomaterials were evaluated using FE-SEM microscope. Solubility enhancement study on both biomaterials were tested using deionized double distilled water. FE-SEM microscopic study showed the particle size differentiation in the ordinary crude biomaterial and nanosized biomaterial. Water solubility studies proved the quick soluble and polydispersibility behaviour of nanosized biomaterial. The solubility enhancement properties of nanosized biomaterials indicated that, when the grain or particle size is reduced, the solubility is enhanced.

Keywords: Ball Milling; Nanoparticles; Biomaterial;