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Article – Journal of Natural Products and Resources

Journal of Natural Products and Resources, Volume 3,Issue 1,2017 Pages 94-96

Antioxidant Activity of Senna alata Root Extracts
B.N. Ita*, G.I. Ndukwe

Senna alata is used traditionally to treat various ailments. The antioxidant potential of acetone, ethanol and aqueous root extracts of Senna alata was studied by measuring its DPPH and ABTS radical scavenging abilities, its ferric reducing power and metal chelating activity as well as its polyphenolics content. The ethanol extract had high content of total phenolics and flavonoids with values of 78.21 mgGAE/g and 39.29 mgQE/g and exhibited the best antioxidant activity in the DPPH and ABTS assays (IC50 = 45.18 and 39.14 μg/mL respectively). In addition, the aqueous extract had more potent metal chelating and reducing power than the other extracts. These results suggest that Senna alata root could serve as new sources of antioxidants that can help prevent oxidative stress.

Keywords: Senna alata Root; Antioxidant Activity; Metal Chelating Activity;